Esses são arquivos pré-compilados. Não há mais nada para instalar, olhando para o README. Você os executa. Primeiro, torne o arquivo executável:
$ chmod +x msmc_linux_64bit
Em seguida, execute:
$ ./msmc_linux_64bit
Usage: msmc [options] <datafiles>
Options:
-i, --maxIterations=<size_t> : number of EM-iterations [default=20]
-o, --outFilePrefix=<string> : file prefix to use for all output files
-r, --rhoOverMu=<double>: ratio of recombination rate over mutation rate. Default=0.25.
-t, --nrThreads=<size_t> : nr of threads to use (defaults to nr of CPUs)
-p, --timeSegmentPattern=<string> : pattern of fixed time segments [default=10*1+15*2]
-P, --subpopLabels=<string> comma-separated subpopulation labels (assume one single population by default, with
number of haplotypes inferred from first input file). For cross-population analysis with 4 haplotypes, 2
coming from each subpopulation, set this to 0,0,1,1
-R, --fixedRecombination : keep recombination rate fixed [recommended, but not set by default]
-I, --indices: indices (comma-separated) of alleles in the data file to run over
-s, --skipAmbiguous: skip sites with ambiguous phasing. Recommended for gene flow analysis
-h, --help: show this message