Tente remover <key>Disabled</key><true/>
AND adicionando <key>RunAtLoad</key><true/>
.
Meu arquivo plist
<?xml version='1.0' encoding='UTF-8'?>
<!DOCTYPE plist PUBLIC "-//Apple Computer//DTD PLIST 1.0//EN"
"http://www.apple.com/DTDs/PropertyList-1.0.dtd" >
<plist version='1.0'>
<dict>
<key>Label</key><string>org.macports.php-fpm</string>
<key>ProgramArguments</key>
<array>
<string>/opt/local/bin/daemondo</string>
<string>--label=php-fpm</string>
<string>--start-cmd</string>
<string>/opt/local/sbin/php-fpm</string>
<string>;</string>
<string>--pid=fileauto</string>
<string>--pidfile</string>
<string>/opt/local/var/run/php-fpm/php-fpm.pid</string>
</array>
<key>Debug</key><false/>
<key>Disabled</key><true/>
<key>OnDemand</key><false/>
</dict>
</plist>
Após a reinicialização, não está sendo carregado automaticamente. Eu ainda tenho que iniciar manualmente o php-fpm. Eu tentei descarregar e adicionar RunAtLoad etc. sem sorte e tentei ambos os comandos launchctl.
sudo launchctl load -F /Library/LaunchDaemons/org.macports.php-fpm.plist
sudo launchctl load -w /Library/LaunchDaemons/org.macports.php-fpm.plist