Sim, você pode, mas terá que converter os discos em "discos dinâmicos" primeiro. De acordo com a Microsoft :
If you convert the disk containing the boot and system partitions to a dynamic disk, you can mirror the boot and system volumes onto another dynamic disk. Then, if the disk containing the boot and system volumes fails, you can start the computer from the disk containing the mirrors of these volumes. For more information, see Create and test a mirrored system or boot volume.