O Foobar2000 é capaz disso se você estiver no Windows.
Funcionalidades:
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- Supported audio formats: MP3, MP4, AAC, CD Audio, WMA, Vorbis, FLAC, WavPack, WAV, AIFF, Musepack, Speex, AU, SND... and more with additional components.
- Gapless playback.
- Full unicode support.
- Easily customizable user interface layout.
- Advanced tagging capabilities.
- Support for ripping Audio CDs as well as transcoding all supported audio formats using the Converter component.
- Full ReplayGain support.
- Customizable keyboard shortcuts.
- Open component architecture allowing third-party developers to extend functionality of the player.
Quodlibet deve ser suficiente para a maioria das outras plataformas.
Quod Libet is a GTK+-based audio player written in Python, using the Mutagen tagging library. It's designed around the idea that you know how to organize your music better than we do. It lets you make playlists based on regular expressions (don't worry, regular searches work too). It lets you display and edit any tags you want in the file. And it lets you do this for all the file formats it supports -- Ogg Vorbis, FLAC, MP3, Musepack, and MOD.
Quod Libet easily scales to libraries of thousands of songs. It also supports most of the features you expect from a modern media player, like Unicode support, multimedia keys, and tag editing.