Para substituir uma placa-mãe com falha por uma nova placa-mãe e depois reconfigurar o Windows para trabalhar com a nova placa-mãe, faça o seguinte:
Turn off the computer.
Replace the existing motherboard with the new motherboard.
Insert your Windows Server 2003 CD in the CD-ROM drive or the DVD-ROM drive, and start the computer from the CD.
When you are prompted To set up Windows now, press ENTER, press ENTER.
Setup looks for any previous installations of Windows Server 2003 on the hard disk and then displays a list of any previous installations that it finds.
Use the arrow keys to select the installation that you want to repair, and then press R to select the To repair the selected Windows installation, press R option.
This will start the repair of your previous Windows Server 2003 installation.
Follow the instructions on the screen, and allow Setup to complete the repair of the previous Windows Server 2003 installation.
Setup installs the HAL, the IDE controller drivers, and any other drivers that the new motherboard must have.
After the repair is completed, reinstall any service packs or hotfixes that you had previously installed.
Fonte: Microsoft KB