A documentação do RedHat THP recomenda permitindo THP na maioria dos sistemas:
THP hides much of the complexity in using huge pages from system administrators and developers. As the goal of THP is improving performance, its developers (both from the community and Red Hat) have tested and optimized THP across a wide range of systems, configurations, applications, and workloads. This allows the default settings of THP to improve the performance of most system configurations. However, THP is not recommended for database workloads.
Portanto, desabilitar THP
em todos os nós não melhorará o desempenho.