Sim, você pode, mas precisa ter uma passagem de DVD ativa.
Vá para a máquina do VirtualBox > Configurações > Armazenamento > Habilite o Passthrough para a unidade de DVD.
To allow an external DVD drive to be recognized by a VirtualBox Virtual Machine (VM) it must be configured in such a way that "passthrough" is enabled. Enabling Passthrough allows the underlying operating system to pass the required commands through to the device that is connected to the Virtual Machine as opposed to the host operating system instance.