Solução encontrada link
Deve usar egd: / dev / urandom, não arquivo, usando / dev / random dar um erro
Aqui está o arquivo mc correto
divert(0)dnl
VERSIONID('$Id: generic-hpux10.mc,v 8.13 2001/05/29 17:29:52 ca Exp $')
OSTYPE(hpux11)dnl
DOMAIN(generic)dnl
define('_X400_UUCP_')dnl
define('_MASQUERADE_ENVELOPE_')dnl
define('MASQUERADE_NAME')dnl
define('confTRY_NULL_MX_LIST','T')dnl
define('LUSER_RELAY','name_of_luser_relay')dnl
define('DATABASE_MAP_TYPE','dbm')dnl
define('_CLASS_U_')dnl
define('LOCAL_RELAY')dnl
define('MAIL_HUB')dnl
TRUST_AUTH_MECH('GSSAPI DIGEST-MD5')dnl
FEATURE(always_add_domain)dnl
MAILER(local)dnl
MAILER(smtp)dnl
MAILER(openmail)dnl
MAILER(uucp)dnl
define('SMART_HOST', 'posta.domain.com')
define('confCACERT_PATH', '/etc/mail/certs')dnl
define('confCACERT', '/etc/mail/certs/domain.com.crt')dnl
define('confSERVER_CERT', '/etc/mail/certs/hpux2.domain.com.crt')dnl
define('confSERVER_KEY', '/etc/mail/certs/hpux2.domain.com.key')dnl
define('confCLIENT_CERT', '/etc/mail/certs/hpux2.domain.com.crt')dnl
define('confCLIENT_KEY', '/etc/mail/certs/hpux2.domain.com.key')dnl
define('confRAND_FILE','egd:/dev/urandom')dnl
D{tls_version}TLSv1
O UseTLS=True