Desde o Windows 10 Build 16215, você tem a capacidade de mudar para o monocormome embutido. É um dos novos filtros de cor para facilitar o acesso, que pode ser alternado pelo Windows + Ctrl + C
Windows 10 now includes color filters at the system level, including filters designed to make it easier for people with color blindness to differentiate between colors like red and green and to make it easier for people with light sensitivity to create and consume content. You can find these new filtering options under Settings > Ease of Access > Color and High Contrast (previously called High Contrast Settings).