Você pode criar um contêiner TrueCrypt , colocar seus dados lá e depois gravar o contêiner. Dessa forma, você vê apenas um arquivo no DVD e pode montar o contêiner posteriormente.
Editar:
Na FAQ :
What will happen when a part of a TrueCrypt volume becomes corrupted?
In encrypted data, one corrupted bit usually corrupts the whole ciphertext block in which it occurred. The ciphertext block size used by TrueCrypt is 16 bytes (i.e., 128 bits). The mode of operation used by TrueCrypt ensures that if data corruption occurs within a block, the remaining blocks are not affected. See also the question 'What do I do when the encrypted filesystem on my TrueCrypt volume is corrupted?