Para responder à sua pergunta mais especificamente. Você pode usar nvidia-settings para mudar o meta-modo. Um fragmento da nvidia-settings --help:
-a, --assign=[ASSIGN]
The ASSIGN argument to the '--assign' commandline option is of the form:
{DISPLAY}/{attribute name}[{display devices}]={value}
This assigns the attribute {attribute name} to the value {value} on the X
Display {DISPLAY}. {DISPLAY} follows the usual {host}:{display}.{screen}
syntax of the DISPLAY environment variable and is optional; when it is
not specified, then it is implied following the same rule as the
--ctrl-display option. If the X screen is not specified, then the
assignment is made to all X screens. Note that the '/' is only required
when {DISPLAY} is present.
{DISPLAY} can additionally include a target specification to direct an
assignment to something other than an X screen. A target specification
is contained within brackets and consists of a target type name, a colon,
and the target id. The target type name can be one of "screen", "gpu",
"framelock", "vcs", "gvi", or "fan"; the target id is the index into the
list of targets (for that target type). The target specification can be
used in {DISPLAY} wherever an X screen can be used, following the syntax
{host}:{display}[{target_type}:{target_id}]. See the output of
'nvidia-settings -q all' for information on which target types can be
used with which attributes. See the output of 'nvidia-settings -q
screens -q gpus -q framelocks -q vcs -q gvis -q fans' for lists of
targets for each target type.
The [{display devices}] portion is also optional; if it is not specified,
then the attribute is assigned to all display devices.
Some examples:
-a FSAA=5
-a localhost:0.0/DigitalVibrance[CRT-0]=0
--assign="SyncToVBlank=1"
-a [gpu:0]/DigitalVibrance[DFP-1]=63