A solução é:
[HKEY_CURRENT_USER\Control Panel\Desktop]
"UserPreferencesMask"=hex(3):90,12,03,80,10,02,00,00
"DragFullWindows"="0"
[HKEY_CURRENT_USER\Control Panel\Desktop\WindowMetrics]
"MinAnimate"="0"
[HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer]
"ShellState"=hex(3):24,00,00,00,3E,28,00,00,00,00,00,00,00,00,00,00,00,00,\
00,00,01,00,00,00,13,00,00,00,00,00,00,00,72,00,00,00
[HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced]
"IconsOnly"=dword:00000001
"ListviewAlphaSelect"=dword:00000000
"ListviewShadow"=dword:00000000
"TaskbarAnimations"=dword:00000000
[HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\VisualEffects]
"VisualFXSetting"=dword:00000003
[HKEY_CURRENT_USER\Software\Microsoft\Windows\DWM]
"AlwaysHibernateThumbnails"=dword:00000000
"EnableAeroPeek"=dword:00000000
Esta configuração - APENAS Suavizar bordas das fontes da tela ATIVO (deve reiniciar o PC)
Testado no Windows 10 1803 build 17134.1