O Google teria bastado:
The 0x80501001 error is a generic "failed to complete action"error. This will usually occur when the detected threat is in a zip file. If the detection was in a zip file there are a few options. You can uncheck "Scan archive files" or uncheck "Scan removable drives". While this may sound risky it is not really since malware can't do anything to harm your computer while it is zipped inside an archive. Another option is to delete the zip file if you really don't need it or if you do need it you can extract it to a folder, scan the folder, remove the detected malware, zip the cleaned folder and save it, then delete the originally infected zip file.